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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIR1
All Species:
12.12
Human Site:
S257
Identified Species:
24.24
UniProt:
Q86X95
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X95
NP_004873.3
450
52313
S257
S
K
H
K
K
H
K
S
S
S
S
S
S
S
S
Chimpanzee
Pan troglodytes
XP_001148591
450
52340
S257
S
K
H
K
K
H
K
S
S
S
S
S
S
S
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535968
475
55209
S261
H
K
K
H
K
N
R
S
P
S
S
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DA19
450
51819
N259
N
K
H
K
K
R
K
N
K
S
P
S
S
S
S
Rat
Rattus norvegicus
Q5U2T8
451
51398
K259
N
K
H
K
K
H
K
K
S
S
S
S
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514863
861
95412
S260
S
K
Q
K
K
H
K
S
S
S
S
S
S
S
S
Chicken
Gallus gallus
Q5ZI03
460
53359
M257
S
K
H
K
K
H
K
M
S
S
S
S
S
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689017
177
20337
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649072
366
43629
L180
E
Q
M
K
E
D
G
L
M
M
K
R
S
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491654
560
65813
D289
K
E
K
R
K
N
K
D
K
K
K
D
K
K
K
Sea Urchin
Strong. purpuratus
XP_794696
488
58217
N245
K
K
R
K
D
K
K
N
M
K
R
R
K
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZ67
595
69129
K321
S
D
K
K
R
K
S
K
K
N
K
R
H
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
84
N.A.
80.2
80.2
N.A.
43.5
70
N.A.
33.3
N.A.
38.4
N.A.
36.4
41.3
Protein Similarity:
100
99.5
N.A.
89.4
N.A.
86
86.6
N.A.
48.3
81.5
N.A.
36.6
N.A.
52.4
N.A.
51.2
56.5
P-Site Identity:
100
100
N.A.
60
N.A.
66.6
86.6
N.A.
93.3
93.3
N.A.
0
N.A.
13.3
N.A.
13.3
26.6
P-Site Similarity:
100
100
N.A.
73.3
N.A.
80
93.3
N.A.
93.3
93.3
N.A.
0
N.A.
33.3
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
9
9
0
9
0
0
0
9
0
0
0
% D
% Glu:
9
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
9
0
42
9
0
42
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
67
25
75
67
17
67
17
25
17
25
0
17
17
17
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
9
0
0
0
0
9
17
9
0
0
0
0
0
% M
% Asn:
17
0
0
0
0
17
0
17
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
9
0
0
9
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
9
9
9
9
9
0
0
0
9
25
0
0
0
% R
% Ser:
42
0
0
0
0
0
9
34
42
59
50
59
67
59
67
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _